Occult HBV reactivation induced by ibrutinib treatment : a case report
| Journal | Volume 78 - 2015 |
| Issue | Fasc.4 - Case reports |
| Author(s) | Patrick de Jésus Ngoma, Benoît Kabamba, Geraldine Dahlqvist, Christine Sempoux, Nicolas Lanthier, Tony Shindano, Eric Van Den Neste, Yves Horsmans |
| Full article |
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| (1) Department of Hepato-gastroenterology, (2) Department of Microbiology, (3) Department of Pathology, (4) Department of Hematology, Cliniques universitaires Saint Luc, Université Catholique de Louvain, Brussels, Belgium. |
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Ibrutinib is a small molecule that has been recently developped for the treatment of B cell malignancies. Common side effects are diarrhoea, nausea, fatigue, infections, neutropenia and thrombocy- topenia. Here we report the first case of Hepatitis B virus reactiva- tion in a 80 years old chronic lymphocytic leukaemia patient receiv- ing ibrutinib, suggesting that such treatment must be associated with HBV screening. (Acta gastroenterol. belg., 2015, 78, 424-426). |
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© Acta Gastro-Enterologica Belgica. PMID 26712054 |
